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DNA Scientists

Joshua Lederberg
  • Determined various bacteria can combine their genetic material
Joshua Lederberg was born in New Jersey on May 23, 1925. He attended public school in New

York City, including the prestigious New York City Stuyvesant High School. He received his bachelor’s degree in zoology from Columbia University. Lederberg went on to study medicine at Columbia as well as in the U.S. Navy. Lederberg never finished medical school, however. Instead, he ventured on to Yale in 1945. Heearned his Ph.D. in zoology from Yale in 1948. During this time he had the opportunity to work with Edward Tatum researching genetic recombination and the organization of the genetic material in bacteria.

This opportunity arose as a result of a paper published by Oswald Avery, Colin MacLeod, and Maclyn McCarty the previous year. The paper specified the chemical nature of DNA and inspired Lederberg to research the possibility of sexual reproduction in bacteria. At the time bacteria were thought to only reproduce asexually. Lederberg’s studies led him to determine various bacteria can indeed combine their genetic material. As a result Lederberg was awarded the Nobel Prize in 1958.

Lederberg went on to work as a genetics professor at the University of Wisconsin and Stanford University. He is currently a professor emeritus of molecular genetics and informatics at The Rockefeller University, New York.

Resources

http://profiles.nlm.nih.gov/BB/Views/Exhibit/narrative/biographical.html

http://nobelprize.org/medicine/laureates/1958/lederberg-bio.html